TMS is fundamentally different from medications and talk therapy, operating through a unique mechanism of action. While medications affect the entire body as they cross the blood-brain barrier, TMS specifically targets the brain areas associated with depression and mood regulation. Because TMS is not a medication, you won’t experience common drug-related side effects like gastrointestinal problems, trouble sleeping, or weight gain. 

Spravato® is an FDA-approved nasal esketamine spray, a more specific form of ketamine designed to treat depression. It is also covered by most major insurances.

Unlike Spravato®, ketamine is not FDA-approved or covered by many insurances.

You don’t need to be on medication to undergo TMS therapy; it can be done alongside your current medications or without any. However, to receive Spravato® therapy, you must be taking an antidepressant medication. Our Greenbrook Care Team can work with you and/or your current healthcare provider to discuss what the best treatment plan is for you. 

TMS therapy and Spravato® are options for patients struggling with depression. Many of our patients have previously tried treatments like talk therapy or antidepressant medication without finding relief, or experiencing difficult-to-manage side effects. There’s no "typical" patient—if you’re suffering or suspect you might have depression, it’s crucial to seek care. We’re here to help, and there’s a good chance we can provide the support you need. Call us to discuss if TMS or Spravato® treatments are right for you. If you are experiencing suicidal thoughts or ideations and need help right away, call or text 988 or go to your nearest emergency room.  

Take our 1-minute assessment to see if our treatments are a good option for you. Upon completion, a member of our team will assess your results and contact you to discuss.